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Welcome to HerHairLossHelp.com! As a woman, losing hair or having thinning hair can be a devastating and often confusing experience. A number of women suffer hair loss whether it be through androgenetic alopecia, alopecia areata, universalis, telogen effluvium, etc. With all of the possible triggers for our hair loss physically and emotionally, sometimes it feels as if it is a constant battle within to stay sane. However, you are NOT alone!

Please be sure to REGISTER AS A MEMBER OF OUR ONLINE COMMUNITY. Our online discussion forum is very active with women who suffer from hair loss from all over the world. Ask a question and most likely you will be overwhelmed by the honest and straightforward answers you will receive. These women are warm and welcoming and sometimes a little looney… We currently have over 78,000 articles concerning hair loss and how women cope with it each day.

We are so glad you are here!

Yours truly,
melanie


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Women’s Hair Loss Survey

Some time ago, the moderators and a few other ladies on the forum participated in a brief survey concerning women’s hair loss… To be honest, I found some of the results to be expected (i.e. stressful life events, medications changing, postpartum, etc.) At this time, I’d like to open the survey up to all of our members so that we all have an opporunity in collecting a consensus of information… The survey will stay open until March 31, 2009. This will allow time for members who don’t visit as frequently to participate… I will post the results of the survey within a “registered members only” forum by the end of April…

At no time during the survey are you asked to provide any self identifying information… We don’t want names or socials… We do ask for your location (by state, not city) for demographic data collection {that sounded official, didn’t it?}. If you should decide to take the survey, please do so honestly… It should only take 15 to 30 minutes of your time…

Click Here to take the survey

Thank you, in advance, for your participation! I’m looking forward to seeing the results!!

melanie

PCOS ~ What blood tests to have done

What blood tests should be done to diagnose Polycystic Ovarian Syndrome (PCOS)?


Many doctors will require the following blood tests be done to successfully diagnose PCOS in a patient:

  • Fasting comprehensive biochemical and lipid panel;
  • 2-hour GTT with insulin levels (also called IGTT);
  • LH:FSH ratio;
  • Total testosterone;
  • DHEAS;
  • SHBG;
  • Androstenedione;
  • Prolactin and
  • TSH

FAQs concerning the diagnosis of PCOS

How should PCOS be diagnosed?

PCOS should be diagnosed by a credible physician who will begin with a basic physical examination. He/she may also want to have an ultrasound done of your ovaries and require a number of blood tests. Be sure to let your physician know if you are experiencing any of the symptoms of PCOS. There are a number of doctors who feel that a woman must have at least three of the symptoms prior to diagnosing PCOS. Other doctors may make the diagnosis based on the emphasis on lack of ovulation.

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How are polycystic ovaries diagnosed by ultrasound?

Ovary ultrasound showing cystic ovaries courtesy of LearningRadiology.com

Ovary ultrasound showing cystic ovaries courtesy of LearningRadiology.com

An ultrasound of the ovaries is usually done by placing a probe into the vagina to view the ovaries. Sometimes, an abdominal ultrasound is done but a transvaginal ultrasound is preferred.

A classic PCOS ovary is enlarged and has a “string of pearls” appearance, where the “pearls” are the cysts. Usually ultrasound diagnosis of polycystic ovaries is made if there are at least 8-10 cysts that are less than 10mm in size on each ovary. The polycystic ovary tends to be enlarged to 1.5-3 times the size of a normal ovary.

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Is it possible to have polycystic ovaries without having the syndrome?

Yes. It is estimated that out of 20 to 30% of women, only 5 to 10% will be diagnosed as having Polycystic Ovary Syndrome based on their symptoms. Having cysts on your ovaries is not a definitive criteria to having PCOS. However, a large number of women with ovarian cysts also display other symptoms hormonally of having a predisposition for PCOS.

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Is it possible to have PCOS without having cysts?

The medical jury is still out on this subject. Some physicians believe that if a woman is exhibiting a number of PCOS symptoms but do not have cysts, that does not necessary mean that they do not have the syndrome. However, it is difficult to make a firm diagnosis of PCOS without the presence of either an increased number of small cysts or ovarian enlargement. Furthermore, in most cases, if a patient is displaying other symptoms, the likelihood of some ovary irregularities.

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Polycystic Ovary Syndrome

How common is PCOS?

It is currently believed that approximately 5 to 10% of women have Polycystic Ovary Syndrome (PCOS). It is the most common hormonal disorder in women of reproductive years and the leading cause in women for infertility. Since many women can have PCOS without exhibiting any symptoms, the actual number of women affected could be as much as 10% more of the population.

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What are the symptoms of PCOS?

Photo of a polycystic ovary courtesy of http://www.ovarian-cysts-pcos.com

Photo of a polycystic ovary courtesy of http://www.ovarian-cysts-pcos.com

Some of the most common symptoms include:

  • Amenorrhea (no menstrual period), infrequent menses, and/or oligomenorrhea (irregular bleeding) Menstrual cycles can often be scant, irregular and infrequent or may also exhibit in the form of spotting throughout the month.
  • Oligo or anovulation (infrequent or absent ovulation) Women with PCOS generally produce an egg but they don’t fully mature. Instead, these immature egg sacs can create ovarian cysts.
  • Hyperandrogenism Women who have PCOS generally also have an increase in serum levels of male hormones such as testosterone, androstenedione, and dehydroepiandrosterone sulfate (DHEAS).
  • Infertility
  • Cystic ovaries Classic PCOS ovaries have a “string of pearls” or “pearl necklace” appearance with many cysts.
  • Enlarged ovaries Polycystic ovaries are usually 1.5 to 3 times larger than normal.
  • Chronic pelvic pain
  • Obesity or weight gain Most commonly referred to as an “apple figure”. PCOS women will generally gain weight primarily in the abdomen and waistline.
  • Insulin resistance, hyperinsulinemia, and diabetes Insulin resistance is a condition where the body’s use of insulin is inefficient.
  • Hirsutism (excess hair) Excess hair growth such as on the face, chest, abdomen, thumbs, or toes.
  • Alopecia (female-pattern baldness or thinning hair) The thinning most commonly occurs on the top of the head.
  • Acne/Oily Skin/Seborrhea
  • Acrochordons (skin tags)

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What causes PCOS?

The exact cause of PCOS is unknown. However, there are studies that may lead us to believe that there may be a genetic link. Just as one may have a genetic predisposition to diabetes, one might also have a disposition to PCOS.

Lace Front Wigs

Most store bought wigs are made by machine or largely made by machine, but hand finished. When a wig is hand made, a pattern of your own head has to be taken and from this, a foundation is made. There are different weights and colours of bases available, but the best is a strong, yet sheer lace, which when lightly stretched against the skin, becomes almost invisible.

A lace fronted wig, will usually be custom made and individual human hairs will be painstakingly knotted in to the tiny holes in the lace, creating a natural looking head of hair. The main advantage to a lace-fronted wig is it enables the wearer to have a natural looking hairline. It is also possible to have any style you may desire and lace wigs tend to be significantly lighter, cooler, better fitting and more comfortable than store wigs.

I would say that 9/10 actors, actresses, models, etc who are wearing additional hair in magazines, on stage or on film, will be wearing lace front wigs or hair pieces.

It is possible to buy lace fronted wigs in stores around the world and I have to say, these bare no resemblance to the type favoured by celebrities. Your average celeb will have paid to use to finest wigmaker, who will have sourced finest European hair, used their expertise to make the foundation fit perfectly, knotted this hair in, in such a way, it looks and acts like real hair and will have chosen lace, which matches that persons’ skin colouring. The wig will then be styled by and maintained by an expert (wig dresser) and the lace replaced as soon as it becomes worn. In real life, the only way, to replicate this look is to have a lace fronted piece made for you - Ladies who have bought ‘off the peg’ lace fronts are usually very disappointed

For Theatre/dancers, the lace is usually left an inch from the hairline, to support the wig, improve fit and help it to last longer in heavy use. Make-up is applied to blend in any areas, which may show. For film/TV (and in real life) it is necessary to cut more of the lace back so it cannot be seen up close, but a fringe (bangs) also helps conceal any lace.

Wigs that have ‘lace fronts’ often require re-fronting. The wig itself (if not bonded) should last for many years if well looked after, but may require a new front every 6mths – 12mths if worn every day. I regularly work on wigs which are older than I am and still look like new because of the care they receive.

sally_miniSally Turney
Resident Wig Expert
HerHairLossHelp.com

Sally’s Not-So-Quick Guide To The Wonderful World Of Wigs

Dear Friends,

I have put this not-so-quick-guide together, to try and steer you through the endless maze of where to start when you are looking to buy a wig. I hope you find it useful,

Sally Turney
Resident Wig Expert
HerHairLossHelp.com

Where to start…

There are so many choices aren’t there? It can be an incredibly daunting experience to buy your first wig. I think the very first question you need to ask is:

Do I really need a wig?

Most people think because I work with wigs, that I must think they are the answer to everybody’s prayers, but the advice I would give to my mother, sister or best friend, is not to go in to one unless you really need to. There is nothing worse than being rushed in to making a decision and I believe it is essential you take the time to do your homework and be fully informed about ALL the options before committing to a wig.

I have seen many women wearing full wigs, who could in fact have been better suited to ¾ pieces or even less, but they didn’t know they were available. I recently saw a lady who had been wearing a topper for 5 years, which she was renting at enormous expense and she didn’t need it at all. She had been told she needed it by a girl in a very successful salon(who in my opinion was more more interested in her commission than doing right by someone), but in fact all she needed was some light cosmetic coverage. There are many options.

Cosmetic Options

This should be your first port of call and probably will be. There are so many great volumising products on the market – shampoos, mousses, serums, lotions – don’t be frightened to experiment and keep a written record of things you like/don’t like and any observations you make about the effect of the products on your hair/scalp. Try concealers like Couvre, dermamatch, Fullmore and Toppik – they all make the hairs appear denser and stop light reflecting off a bare scalp. Cosmetic options often take skill and practice to perfect, but many people find them enormously useful.

Extensions

For many people, this is the next step. Again, I would urge anyone who is contemplating extensions to really do their homework and be very selective in whom they go to. The whole subject of extensions is one that I tend to shy away from, because I have seen more harm than good come of them, but I do accept, for many women, who have got the balance right, they are a life line. If the extensions are too heavy or left for too long, they can cause traction Alopecia, which is a trend now amongst celebrities who are wearing long, heavy extensions and almost permanently. They can also be very expensive, as you not only pay for the initial setting up, but regular refreshings and these are sometimes required as often as every fortnight.

Hats With Hair

It is possible to buy a hat, which comes with synthetic hair. Sometimes this is sewn in, sometimes this is attached with Velcro and you can put it in to other hats. A great idea for when you need to pop something on super quick – to answer the door for instance. I particularly like the hats with hair, for children. They are relatively cheap to purchase and there are lots of shops that sell them on line.

Hair Pieces/Add ons

Unfortunately for many women, a full wig is their first step, instead of a last resort, which I would prefer it to be. Girls, don’t rush it, please look at all the other options first.

There are many hairpieces available to purchase and these are also known as toppers, units, systems, enhancers, wiglets, falls, add ons, etc. They vary greatly in price and quality, starting from low-end pieces, which you could buy on market stalls, thro to custom made pieces from the finest wig makers. So you are looking at spending anywhere from £1 to £1000.

Pieces are attached in a variety of ways, from glue, to clips to bands to Velcro to grips to being weaved in…the list of possibilities is endless.

Synthetic pieces tend to be more popular because they are significantly cheaper and easier to cope with in how you care for them. They are easy to buy - you can cut them down if required and do a bit of D.I.Y on them and you won’t go far wrong. The down side is that they are heavier and hotter and as they are made of an artificial medium, they will never be perfect.

Human hair pieces are a different ball game, better fitting (when they are custom/hand made) lighter, shinier, easier to handle, but price wise they are coming in at a premium and need more care, but the quality…again…depends on the hair you buy!!! Ugh, this subject is so complicated!!

When Is Human Hair Not Human Hair?

When it has had all its ‘human’ qualities removed. This is a process of removing the cuticle, which truly PAINS me to say, has become incredibly popular over the last decade. The result is hair you can (Wha Hey!) sleep in and swim in and that is light, but won’t tangle. It will also look dead and flat (it has no cuticle to reflect shine) and will need silicones etc to make it look like the hair it was once!

Hair Integrations

These are similar to hairpieces, but have a section of elastic webbing, which, once the little piece is in place, you would then slide your own hair through the spaces in between to ‘integrate’ with the piece. Sometimes you can do this at home, but it is big business for salons, producing these systems and either sewing or micro linking these in – there are lots of different ways it can be done. In my experience, integrations look superb at first, but for the wearer they are uncomfortable, it can be hard to wash hair properly, regular salon visits will be required and as you will be wearing it 24/7, you will find it will wear out quickly. Traction Alopecia is also an issue here…sorry!

Wigs

Wigs vary in price from about £20 from a very low-end dress up wig to £6,000 for a high-end human hair wig. What’s the difference? It’s STAGGERING!!

Synthetic Wigs

These are improving and the ranges are getting better and better every year. Care is minimal and you can play with these wigs and make mistakes without too serious repercussions. The only big NO NO is heat and this includes heat from bedside lights, an oven etc that will melt the artificial fibres and cause frazzling.

Because of the artificial materials used, they tend to be hot, heavy and itchy and you really need to wear a wig liner, tho few people do. Fit can be an issue too.

Cheaper wigs will be all wefted, which is rows of hair sewn together, which leaves big gaps. More expensive wigs will be monofilament or part monofilament, designed so it looks like the hair is growing out of the scalp. You can also purchase synthetic wigs, which have a micro skin top. Here, the hair is tied in to a nylon base and a coating of thin latex is applied, creating the effect of a natural scalp/parting.

With regards to size, synthetic wigs all come with Velcro tabs, which are helpful for improving fit. Fortunately most women have an average size head and can therefore fit the majority of wigs, which cater for this size (21-22.5”). If in doubt you can measure your head with a tape measure going around the forehead at the hairline, under the hair, behind the ears and around the nape of the neck. If this is too difficult to do by yourself, it’s a good idea to have someone help you.

Most people choose wigs, which are closest to their natural style, but when shopping for a wig also take in to consideration how easy the wig will be to look after, your face shape, eye colour and complexion (with and without make-up). Whilst there is always a great temptation to steer away from your ‘old’ hair and go for something dramatically different, in my experience this rarely works, as women just want to look ‘normal’ and not stand out in a crowd.

Human Wigs

Again, can be purchased off the rack or hand made. Sometimes you can buy blends of both synthetic and human. If you are having a wig made for you, this will usually involve three visits – one for a consultation and to make a mould of your head, one to check the foundation (base) for fit and one to collect the wig. Sometimes they are all one length (a la cousin ITT!) and require you to take them to a good salon to be cut and sometimes they are ready to wear.

Bases tend to vary from cotton type bases to suction bases to coarse nets to finest lace bases…. Ideally you want a very light base, which will let as much air thro as possible.

If a competent wig maker has measured you, the wig will fit well, but you may like to use double sided tape or glue (which comes in every conceivable type and strength you can imagine). You can wear the wig all day, over night, for a few days or for a few weeks, but note with the latter, we are talking about bonding and extra precautions are necessary.

It is possible to sleep/swim in your wig, although most women choose not to because of the expense of replacing it. Many women buy two human hair wigs and wear them in rotation.

Repairs are sometimes necessary and good handling is essential to maintain the longevity of the wig. Fine lace bases can snag easily and will need repairing straight away to prevent tearing.

The disadvantages to buying human hair hand made wigs are simple – they are more expensive and more care is required in terms of looking after them. If you are sold a human hair wig, you WILL be told you need special tools and Equipment. I was recently contacted by a lady who had bought £500 worth of ‘essentials’ from a reputable wig maker. In actual fact, the real cost she should have paid is about £70.

The advantages? You can have anything made from the size of a penny up to a full head of hair and fit should be perfect as it is designed for you. You can have any colour, any density, any length, any texture and you can style it as your own. If you are having European, Virgin hair, you should be prepared to work at keeping it looking good. Often when your wig arrives it is not looking as good as it could and you need to be prepared to get it in to condition for a couple of weeks (this is because of the chemical processes the hair itself is put thro).

The wig will be light, airy, cooler than anything else you could have and if used with bonding can be worn 24/7, swam and slept in.

In Summary

The subject is enormously complicated and I have barely scratched the surface of the endless list of possibilities, but rest assured if your desire is to have a natural head of shiny, bouncy hair, which is comfortable and ‘part of you’ – it can be done, but what you put in, you will get out and I want you to avoid making expensive mistakes. People WILL always try to sell you things you don’t need and for every single piece of advice you receive from now on, I want you to ask yourself ‘Does this person have anything to gain?’ Almost all wig salons/people/stores/shops/consultants have some vested interest in steering you towards buying something.

I do not sell anything EVER nor do I promote anything. I am here in the UK and 99% of the people I advise are overseas. You know what…I have a vested interest too! It’s true! I have a vested interest in each and every one of you and giving you the most honest advice I can, because when you feel good, I feel good!

Scarring Alopecia - All Flared Up! {video}

My thanks go out to MoDolly, who has gone above and beyond to get the word out about scarring alopecia. More women need to know the symptoms and treatment options available!!

melanie

Hypothyroidism and Thyroid Hairloss

    Claire, one of our lovely moderators on the forum, put together this incredibly informative post on hypothyroidism, TSH levels and doctors…

Just a little background. I was diagnosed with Hypothyroid in June of 2005. After over a year of fighting with doctors I finally reached a TSH level below 3.0 in August of 2006.

I am not a doctor, nor a health professional. I’ve read, experimented, and suffered through this thyroid maze. As I would say if you came to me with someone else information, please take everything I say about my treatment with a grain of salt. What works for me may not work for you, but I feel it’s important to give you an idea of what can be done.

The reason I had so much trouble with doctors is that many of them have been out of med school longer than the newest findings.

As of 2002 the AACE (American Association of Clinical Endocrinologists) published new findings on the correct thyroid levels in most individuals. No longer is the range between .5 and 5.0 but a smaller range of .3 to 3.0

aaceThe full AACE Guidelines can be viewed by clicking this link.

What does this mean? That many many doctors are under treating their patients. Even more frightening is that there are doctors who have not been updated on thyroid function for an even longer period of time and think that a TSH level under 10 is appropriate. Luckily those doctors are few and far between. What this teaches us is that educating oneself on ones health matters is most important. We assume that doctors are knowledgable about all health matters. The truth is, scientists and specialists come to new findings every year and general practitioners are the last to know. Doctors are well educated on health matters, unfortunately, they are well educated within the time frame in which they went to medical school. This leaves several years of updated information that they have not had access too. Even more frightening is that many of them dismiss new findings if such information is brought to them by a patient.

synthroidIf you are hypothyroid and still suffering with symptoms and your doctor is telling you that your thyroid is functioning normally it is time to start taking control of your situation.

First, obtain a copy of your most recent lab work. Find out what your thyroid levels really are. Second approach your doctor about what issues you are having. If he is unwilling to listen, then you have a couple of options.
A. you can take in a copy of the AACE’s newest research {http://www.aace.com/public/awareness/tam/2004/tsh.php}, a copy of a checklist of your symptoms {http://thyroid.about.com/cs/hypothyroidism/a/checklist.htm}

If you have any other symptoms that seem abnormal to you, but are not listed, please list them as well. Recently, I’ve discovered that overnight leg cramps is also a symptom of hypothyroid.

B. you can switch doctors.

You may have to do B. anyway, if your doctor is unwilling to work with you. The best thing you can do is request to be sent to an endocrinologist. If your doctor is unwilling to refer you, you are not without hope. Most insurance companies have patient outreach programs. Obtain a copy of your records, including blood tests ( you have the RIGHT, buy law to get copies of your medical records), a copy of the AACE’s findings, a list of ongoing symptoms and a letter requesting referal to see a specialist. It is possible to go over your doctor’s head in order to do this. You can also switch doctors and request this of your newest doctor. Be warned, even some endocrinologists go by an older TSH scale. If you find this to be so, request a second opinion.

Most important, do not think that the doctor knows more than you. You, and only you truly knows how you feel. Do not worry about offending your doctor. As it is, your doctor doesn’t seem to worry about offending you. You are the boss in this situation. He works for you, if he is unwilling to do his job, then you’ve every right to hire someone else.

Once you find someone willing to work with you ( and if you already have, thank your lucky stars) do not expect your symptoms to eleviate as soon as you start a new dosage. Do not expect your symptoms to eleviate as soon as you reach a healthy TSH level. It’s going to take some time for your body to begin to heal itself. However, you will notice some changes within weeks.

Anatomy image of the thyroid gland courtesy of UpToDate.com

Anatomy image of the thyroid gland courtesy of UpToDate.com

The Thyroid also changes with time. As you begin to reach a healthier TSH level things may plateau and you may have to adjust your meds as needed. It’s not uncommon to reach a healthy TSH level and a few weeks later begin to feel bad. It’s important that within the first year of reaching a healthy TSH goal to be checked every 3 months. After that it’s important to be tested twice a year. Some doctors say only once a year is enough, this is not true. Thyroid levels change with temperature changes. One of the best ideas is to check your thyroid levels a few weeks into the first cold snap of winter and within the first few weeks of summer heat. Many thyroid patients find they need to adjust their dose with the extreme temperatures of both seasons. Cold weather slows thyroid function, hot weather tends to call for less thyroid supplement.

It is also not uncommon for a short period of time in which you have a few of the sensations associated with HypERthyroid upon starting a new dosage. I’ve found the best way to avoid this is to titer up. My doctor is willing to work with me on this. This consists of me cutting pills and slowly adding till I reach my newest dosage level. Thyroid hormone takes time to build within the system. This is why titering up works in many cases. This is also why you do not retest your thyroid till 6-8 weeks after beginning a new dose. If you decide to titer up, do not retest till the 6-8 week mark after you reach your INTENDED dosage. My pm box is always open if you have additional questions about this. It is important to discuss this with your doctor as well. Do not raise your dosage above what he recommends till you’ve had your TSH checked. Then be sure to inform him of anything you intend to do, so that you may have another test lined up.

There is no magic number. Not when it comes to TSH, not when it comes to dosage. The ideal setting is for you and your doctor to work together by using both blood work and how you feel.

When taking thyroid meds it’s important to understand a couple of things. First, any food or vitamins taken with the thyroid med will change the absorption rate of the hormone. Your best bet is to take the thyroid med first thing in the morning and an hour before and after eating. So, no food for an hour on either side of taking your med. Even more important is delaying the taking of vitamins. Especially iron and calcium. Both of those can have an effect on the way your body absorbs the thyroid hormone. It is best to take your vitamins either in the middle of the day ( 2-3 hours) after your hormone or at night ( 6-8 hours) before.

If, you are the type that has to eat first thing in the morning then know that you must follow the pattern every day. If you eat less than an hour after taking your thyroid hormone then it is important to follow this habit daily. It is also important to stick to a similar breakfast food. For instance if you drink milk, it will have an effect on how your body absorbs the hormone, so it’s important to have dairy at the same time, every day as to keep the hormone absorption similar.

Cipro Interacts with Thyroid Medication

Popular Antibiotic Interacts with Thyroid Medication

The British Medical Journal has reported on a several cases of unexplained hypothyroidism in thyroid patients (on levothyroxine) who were taking the popular antibiotic ciprofloxacin. Ciprofloxacin is the generic name for the fluoroquinolone antibiotic sold under the brand names Cipro, Ciproxin and Ciprobay, Cirpoxine, and Ciflox. The drug is primarily used to treat urinary tract infections, pneumonia, and sexually transmitted diseases. Ciprofloxacin was also in the news during the anthrax scare, given its use in treatment for anthrax exposure.
What the researchers found in these cases were evidence that oral ciprofloxacin interacts with levothyroxine (i.e., Synthroid, Levoxyl, Levothroid) if taken together. It’s thought that the ciprofloxacin may somehow decrease the absorption of the levothyroxine.

In one case, a woman taking 125 mcg a day of levothyroxine took ciprofloxacin (750 mg twice a day) and her TSH level rose to 44 after four weeks. Even when her dosage was raised to 200 mcg a day, her TSH didn’t respond. Only when the ciprofloxacin was stopped did the TSH return to normal. In another case, a woman who was stabilized on 150 mcg a day of levothyroxine saw her TSH go from 1.6 to 19 after 3 weeks of treatment with ciprofloxacin at 500 mg twice a day.

What Can You Do?

If you’re a thyroid patient who is taking ciprofloxacin, what should you do?

The research suggested that thyroid tests were normalized if patients took the levothyroxine and ciprofloxacin at least six hours apart.

So, if you are on levothyroxine, it makes sense to allow at least six hours apart from taking your ciprofloxacin. And if you have to take the antibiotic for a lengthy period, you should discuss the potential impact on your thyroid with your doctor, and possibly request period thyroid testing to ensure that your thyroid treatment is not affected.

Source: Cooper, John, “Ciprofloxacin interacts with thyroid replacement therapy,” British Medical Journal, 2005

Thyroid levels affect Alzheimer’s risk - study

WASHINGTON (Reuters) - Women with low or high levels of a hormone that affects thyroid gland function and thyroid hormone levels may have a higher risk of Alzheimer’s disease, researchers reported Monday.

While it is not clear whether Alzheimer’s affects thyroid function or the other way around, the findings dovetail with long-standing knowledge that having an underactive or overactive thyroid can affect memory.

Dr. Zaldy Tan of Hebrew SeniorLife, Beth Israel Deaconess Medical Center and Harvard Medical School in Boston and colleagues looked at measured levels of a thyroid-regulating hormone called thyrotropin in 1,864 healthy men and women with an average age of 71.

They had blood drawn as part of the larger Framingham Health Study in which practically everyone in a Massachusetts town has had their health scrutinized for decades.

Writing in the journal Archives of Internal Medicine, Tan and colleagues said 209 of the volunteers had developed Alzheimer’s disease after nearly 13 years.

Women with the lowest and highest levels of thyrotropin had more than double the risk of developing Alzheimer’s disease. No such relationship was seen in men.

Changes in the brain caused by Alzheimer’s disease may reduce the amount of thyrotropin released, Tan’s team said. Alternately, low or high thyrotropin levels could damage brain cells or blood vessels.

They said the findings should be tested in a larger population. (Reporting by Maggie Fox; editing by Todd Eastham)

Source: Reuters North American News Service